Skin lymphomas
Mycosis Fungoides is a T épidermotrope lymphoma. It's the main cutaneous lymphoma.
In the beginning, it manifests itself by red plates, sometimes finely squamous and a little atrophic (corresponding to the denomination "parapsoriasis in Plaques").
These plates can regress and become permanent, intensify and infiltrate irregularly in several months or years and then appear real tumors whose resemblance with fungi justifies the curious name of "Mycosis Fungoides "given in 1806 by the French dermatologist J.-L Alibert.
At the same time can be affected by lymph nodes and, in highly evolved forms, organs such as the lung.
This disease can last 10 or 20 years from the onset of the first signs.
A variety "erythrodermic " of the Mycosis fungoides, which is characterized by the red coloration of the whole coat, evolves more rapidly and responds less well to the treatments.
Sezary's disease is related to the proliferation of T cells, present in the skin but also in the blood (circulating Sezary cells).
Mycosis fungoides and Sezary disease are rare ailments. They occur in the second half of life, a little more often in men than in women.
The local treatments are limited to the skin: total superficial radiation (electron therapy), dyeing with solutions of cytotoxic drugs such as Chlormethine (caryolysine), ultraviolet rays a associated with a product Photosensitizing (PUVA), corticosteroid ointments.
It is also possible to implement general treatments: chemotherapy or interferon.
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